Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation
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چکیده
منابع مشابه
Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1
OBJECTIVE TLR7 ligation in plasmacytoid dendritic cells is promising for the treatment of cancer, allergy, and infectious diseases; however, high doses of ligands are required. We hypothesized that the combination of structurally different TLR7 ligands exponentiates the resulting immune response. METHODS CAL-1 (human pDC line) cells were incubated with the TLR7-specific adenine analog CL264 a...
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ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2018
ISSN: 0818-9641,1440-1711
DOI: 10.1111/imcb.12173